Binimetinib for the treatment of NRAS-mutant melanoma.

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Binimetinib for the treatment of NRAS-mutant melanoma.

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Binimetinib for the treatment of NRAS-mutant melanoma.

@en

type

Item

label

Binimetinib for the treatment of NRAS-mutant melanoma.

@en

prefLabel

Binimetinib for the treatment of NRAS-mutant melanoma.

@en

P1476

Binimetinib for the treatment of NRAS-mutant melanoma

@en

P2093

Paola Queirolo

http://www.w3.org/2001/XMLSchema#string

P2860

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study

Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta-analysis.

NRAS mutation status is an independent prognostic factor in metastatic melanoma.

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.

MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study.

Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo.

Improved overall survival in melanoma with combined dabrafenib and trametinib.

Mutations of the BRAF gene in human cancer

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

Distinct sets of genetic alterations in melanoma

P304

985-990

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P31

scholarly article

P356

10.1080/14737140.2017.1374177

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Francesco Spagnolo

P577

2017-09-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28851243

http://www.w3.org/2001/XMLSchema#string

Binimetinib for the treatment of NRAS-mutant melanoma.

about

Binimetinib for the treatment of NRAS-mutant melanoma.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698