about
Potential of epigenetic therapies in the management of solid tumorsThe role of epigenetics in kidney malignanciesAlterations of Epigenetic Regulators in Pancreatic Cancer and Their Clinical ImplicationsEpigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?Targeting BET bromodomains for cancer treatmentGenomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence.Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationLoss of nucleolar histone chaperone NPM1 triggers rearrangement of heterochromatin and synergizes with a deficiency in DNA methyltransferase DNMT3A to drive ribosomal DNA transcription.Genetic alterations of histone lysine methyltransferases and their significance in breast cancerTargeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas.Exome Sequencing in Classic Hairy Cell Leukaemia Reveals Widespread Variation in Acquired Somatic Mutations between Individual Tumours Apart from the Signature BRAF V(600)E Lesion.KDM4A, KDM4B and KDM4C in non-small cell lung cancer.Targeting epigenetic regulations in cancerAn integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancerReading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.Structural analysis of an active fungal PRC2.Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.Chromatin remodeler mutations in human cancers: epigenetic implications.Mutation of cancer driver MLL2 results in transcription stress and genome instability.The molecular hallmarks of epigenetic control.Loss of expression of 5-hydroxymethylcytosine in CD30-positive cutaneous lymphoproliferative disorders.The number of key carcinogenic events can be predicted from cancer incidenceClinical and molecular insights into adenoid cystic carcinoma: Neural crest‐like stemness as a target.Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine.Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations.Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice.Clinical and molecular insights into adenoid cystic carcinoma: Neural crest-like stemness as a target.Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression.Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified.Composition and Function of Mutant Swi/Snf Complexes.The DNMT3A R882H mutant displays altered flanking sequence preferences.New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update.Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression.Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics.Association of TET3 epigenetic inactivation with head and neck cancer.The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexesEffects of chidamide and its combination with decitabine on proliferation and apoptosis of leukemia cell linesGenomics of adult and pediatric solid tumors
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Driver mutations of cancer epigenomes.
@en
type
label
Driver mutations of cancer epigenomes.
@en
prefLabel
Driver mutations of cancer epigenomes.
@en
P2860
P1433
P1476
Driver mutations of cancer epigenomes
@en
P2093
David M Roy
Timothy A Chan
P2860
P2888
P304
P356
10.1007/S13238-014-0031-6
P577
2014-03-14T00:00:00Z
P5875
P6179
1036494552