Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors. - Wikidata - wikimedia - TriplyDB

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.

http://www.wikidata.org/entity/Q38673602

about

Heritable Cancer Syndromes Related to the Hypoxia Pathway Epigenetics and Cellular Metabolism Molecular markers of paragangliomas/pheochromocytomas Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine.Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.SDHB deficiency promotes TGFβ-mediated invasion and metastasis of colorectal cancer through transcriptional repression complex SNAIL1-SMAD3/4.Altered Mitochondrial Signalling and Metabolism in Cancer.The emerging role and targetability of the TCA cycle in cancer metabolism.Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy.Molecular Pathogenesis and Diagnostic, Prognostic and Predictive Molecular Markers in Sarcoma.High nuclear expression of proteasome activator complex subunit 1 predicts poor survival in soft tissue leiomyosarcomas.IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas.Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas.Metformin targets histone acetylation in cancer-prone epithelial cells.Cofactors As Metabolic Sensors Driving Cell Adaptation in Physiology and Disease.Targeting Metabolism for Cancer Therapy.AKT as Locus of Hydrogen Bond Network in Cancer.Biochemical Characterization of Two Clinically-Relevant Human Fumarase Variants Defective for Oligomerization.Identification of a metabolic disposal route for the oncometabolite S-(2-succino)cysteine in Bacillus subtilis.Metabolic Plasticity of Tumor Cell Mitochondria

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P2860

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.

http://www.wikidata.org/entity/Q38673602

description

2015 nî lūn-bûn

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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Inactivation of SDH and FH cau ...... toma and smooth muscle tumors.

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type

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Inactivation of SDH and FH cau ...... toma and smooth muscle tumors.

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prefLabel

Inactivation of SDH and FH cau ...... toma and smooth muscle tumors.

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ONCOTARGET.6091

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Inactivation of SDH and FH cau ...... ytoma and smooth muscle tumors

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Attje S Hoekstra

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Cees J Cornelisse

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Cor Ras

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Esther Korpershoek

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Henricus P M Kunst

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Inge H Briaire-de Bruijn

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Ivonne van Minderhout

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Jean-Pierre Bayley

http://www.w3.org/2001/XMLSchema#string

Johnny Suijker

http://www.w3.org/2001/XMLSchema#string

Marieke A de Graaff

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P2860

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Histone demethylation by a family of JmjC domain-containing proteins.

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

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10.18632/ONCOTARGET.6091

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36

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Judith Vmg Bovée

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2015-11-01T00:00:00Z

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282912064

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phaeochromocytoma

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