Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity.
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Many stimuli pull the necrotic trigger, an overviewInterplay between Inflammation and Cellular Stress Triggered by Flaviviridae VirusesTLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.Nucleoside diphosphate kinase and flagellin from Pseudomonas aeruginosa induce interleukin 1 expression via the Akt/NF-κB signaling pathways.Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular.Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain InjuryThe serine threonine kinase RIP3: lost and found.Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3.Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection.Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell deathAIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and non-canonical pathways.Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.Apoptosis-associated speck-like protein containing a CARD forms specks but does not activate caspase-1 in the absence of NLRP3 during macrophage swelling.Striated muscle activator of Rho signaling is required for myotube survival but does not influence basal protein synthesis or degradation.Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages.T3SS effector ExoY reduces inflammasome-related responses by suppressing bacterial motility and delaying activation of NF-κB and caspase-1.Effect of erythropoietin on primed leucocyte expression profile.AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.Differential effects of colchicine in blood mononuclear cells of patients with Behçet disease in relation to colchicine responsiveness.The Canonical Inflammasome: A Macromolecular Complex Driving Inflammation.
P2860
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P2860
Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Caspase-1 protein induces apop ...... tly of its catalytic activity.
@en
type
label
Caspase-1 protein induces apop ...... tly of its catalytic activity.
@en
prefLabel
Caspase-1 protein induces apop ...... tly of its catalytic activity.
@en
P2093
P2860
P356
P1476
Caspase-1 protein induces apop ...... ntly of its catalytic activity
@en
P2093
Hiroko Kushiyama
Kou Motani
Ryu Imamura
Takashi Suda
Takeshi Kinoshita
P2860
P304
33963-33972
P356
10.1074/JBC.M111.286823
P407
P577
2011-08-08T00:00:00Z