Design and Synthesis of Potent and Selective PIM Kinase Inhibitors by Targeting Unique Structure of ATP-Binding Pocket.

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Design and Synthesis of Potent and Selective PIM Kinase Inhibitors by Targeting Unique Structure of ATP-Binding Pocket.

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

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name

Design and Synthesis of Potent ...... ructure of ATP-Binding Pocket.

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type

Item

label

Design and Synthesis of Potent ...... ructure of ATP-Binding Pocket.

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prefLabel

Design and Synthesis of Potent ...... ructure of ATP-Binding Pocket.

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P1476

Design and Synthesis of Potent ...... ructure of ATP-Binding Pocket.

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P2093

Hirofumi Nakano

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Hirotatsu Kojima

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Takayoshi Okabe

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Tetsuo Nagano

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Tsukasa Hasegawa

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P2860

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor

Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound

Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases

Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinica

Pim kinase inhibitors: a survey of the patent literature

Small molecule inhibitors of PIM1 kinase: July 2009 to February 2013 patent update

Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.

P304

504-509

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.6B00518

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P433

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P478

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P577

2017-04-03T00:00:00Z

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P698

28523101

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P921

binding pocket

P932

5430388

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