Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors. - Wikidata - wikimedia - TriplyDB

Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.

Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.

http://www.wikidata.org/entity/Q38682140

about

Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets Regulators of Cholangiocyte Proliferation.Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology.Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis.Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth Functional and structural features of cholangiocytes in health and disease.Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats.Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms.Chronic nicotine exposure stimulates biliary growth and fibrosis in normal rats Recent advances in the morphological and functional heterogeneity of the biliary epithelium Therapeutic actions of melatonin on gastrointestinal cancer development and progression.Melatonin regulation of biliary functions.Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes.Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth.Mechanisms of cholangiocyte responses to injury.Melatonin Alleviates Liver Apoptosis in Bile Duct Ligation Young Rats.Prolonged administration of secretin to normal rats increases biliary proliferation and secretin-induced ductal secretory activity.Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation.Melatonin suppresses activation of hepatic stellate cells through RORα-mediated inhibition of 5-lipoxygenase.Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease Recent advances in understanding bile duct remodeling and fibrosis

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Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.

http://www.wikidata.org/entity/Q38682140

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Melatonin inhibits cholangiocy ...... t not MT2 melatonin receptors.

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type

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Melatonin inhibits cholangiocy ...... t not MT2 melatonin receptors.

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Melatonin inhibits cholangiocy ...... t not MT2 melatonin receptors.

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AJPGI.00206.2011

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American Journal of Physiology - Gastrointestinal and Liver Physiology

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Melatonin inhibits cholangiocy ...... ut not MT2 melatonin receptors

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P2093

Anastasia Renzi

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Eugenio Gaudio

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Fanyin Meng

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Gianfranco Alpini

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Heather Francis

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Julie Venter

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Mellanie White

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Shannon Glaser

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Sharon Demorrow

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Yoshiyuki Ueno

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P2860

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor

The melatonin receptor subtype MT1 is expressed in human gallbladder epithelia

The circadian clock component BMAL1 is a critical regulator of p21WAF1/CIP1 expression and hepatocyte proliferation

Melatonin in humans

Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.

After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes.

Melatonin ameliorates liver fibrosis induced by bile-duct ligation in rats.

Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway.

Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation.

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10.1152/AJPGI.00206.2011

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4

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301

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Domenico Alvaro

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Antonio Franchitto

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2011-07-14T00:00:00Z

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51493441

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