Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development
about
Rapid and accurate in silico solubility screening of a monoclonal antibody library.Preferential interactions of trehalose, L-arginine.HCl and sodium chloride with therapeutically relevant IgG1 monoclonal antibodies.In-silico prediction of concentration-dependent viscosity curves for monoclonal antibody solutions.Biopharmaceutical Informatics: supporting biologic drug development via molecular modelling and informatics.Monoclonal antibodies: formulations of marketed products and recent advances in novel delivery system.Challenges for the pharmaceutical technical development of protein coformulations.Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineeringChallenges in Predicting Protein-Protein Interactions from Measurements of Molecular DiffusivityPredicting protein-protein interactions of concentrated antibody solutions using dilute solution data and coarse-grained molecular models.Specific optical rotation is a versatile tool for the identification of critical micelle concentration and micellar growth of tartaric acid-based diastereomeric amphiphiles.Theory for the Liquid-Liquid Phase Separation in Aqueous Antibody Solutions.Weak IgG self- and hetero-association characterized by fluorescence analytical ultracentrifugation.
P2860
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P2860
Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Molecular basis of high viscos ...... ation drug product development
@en
type
label
Molecular basis of high viscos ...... ation drug product development
@en
prefLabel
Molecular basis of high viscos ...... ation drug product development
@en
P2093
P2860
P1476
Molecular basis of high viscos ...... ation drug product development
@en
P2093
Dheeraj S Tomar
Sandeep Kumar
Satish K Singh
Sumit Goswami
P2860
P304
P356
10.1080/19420862.2015.1128606
P577
2016-01-06T00:00:00Z