Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient.

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Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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Cellular effect and efficacy o ...... ar net concentration gradient.

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Cellular effect and efficacy o ...... ar net concentration gradient.

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Cellular effect and efficacy o ...... ar net concentration gradient.

@de

Cellular effect and efficacy o ...... ar net concentration gradient.

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Cellular effect and efficacy o ...... ar net concentration gradient.

@de

Cellular effect and efficacy o ...... ar net concentration gradient.

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P1476

Cellular effect and efficacy o ...... ar net concentration gradient.

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P2093

Anja Seckinger

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Dirk Theile

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Johanna Weiss

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Julia Schäfer

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Jürgen Burhenne

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Lukas Welti

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P2860

The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5

Carfilzomib in multiple myeloma patients with renal impairment: pharmacokinetics and safety

Therapeutic landscape of carfilzomib and other modulators of the ubiquitin-proteasome pathway.

Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

New proteasome inhibitors in myeloma.

Carfilzomib.

Proteasome inhibition correlates with intracellular bortezomib concentrations but not with antiproliferative effects after bolus treatment in myeloma cell lines.

Ricolinostat (ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death.

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters.

The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4.

P2888

s00280-017-3335-4

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71-79

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scholarly article

P356

10.1007/S00280-017-3335-4

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P577

2017-05-12T00:00:00Z

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P6179

1085403064

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P698

28500557

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