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Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current SolutionsConvergent biosynthetic pathways to β-lactam antibioticsBeyond Traditional Antimicrobials: A Caenorhabditis elegans Model for Discovery of Novel Anti-infectivesCARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance databaseAntibacterial Nucleoside-Analog Inhibitor of Bacterial RNA PolymeraseThe Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor.The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets.EpideMiology and control measures of outBreaks due to Antibiotic-Resistant orGanisms in EurOpe (EMBARGO): a systematic review protocol.The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase.Multidrug-resistant bacteria compensate for the epistasis between resistances.A cross-metathesis approach to novel pantothenamide derivatives.Thusin, a Novel Two-Component Lantibiotic with Potent Antimicrobial Activity against Several Gram-Positive PathogensCombinatorial strategies for combating invasive fungal infections.Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus.Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.Rapid screening for specific glycosylation and pathogen interactions on a 78 species avian egg white glycoprotein microarrayCurative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies.Contemporary challenges and opportunities in the diagnosis and outbreak detection of multidrug-resistant infectious disease.Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy.From bench to bed and back again: phage therapy of childhood Escherichia coli diarrhea.An update on the use of C. elegans for preclinical drug discovery: screening and identifying anti-infective drugs.Exploiting the porin pathway for polar compound delivery into Gram-negative bacteria.Toolbox for Antibiotics Discovery from Microorganisms.New Found Hope for Antibiotic Discovery: Lipid II Inhibitors.Recent Advances in the Rational Design and Optimization of Antibacterial Agents.Bacterial fatty acid metabolism in modern antibiotic discovery.Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes.Antimicrobial resistance surveillance in the genomic age.Bacterial proteases, untapped antimicrobial drug targets.Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health.Human lung ex vivo infection models.Genetic Regulation of Virulence and Antibiotic Resistance in Acinetobacter baumanniiResistance diagnosis and the changing economics of antibiotic discovery.Next-generation approaches to understand and combat the antibiotic resistome.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity.The advancement of multidimensional QSAR for novel drug discovery - where are we headed?Identification of the Biosynthesis Gene Cluster for the Novel Lantibiotic Paenilan from Paenibacillus polymyxa E681 and Characterization of its Product.Development and use of personalized bacteriophage-based therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii infection.
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Antibacterial drug discovery in the resistance era.
@en
type
label
Antibacterial drug discovery in the resistance era.
@en
prefLabel
Antibacterial drug discovery in the resistance era.
@en
P356
P1433
P1476
Antibacterial drug discovery in the resistance era.
@en
P2093
Eric D Brown
Gerard D Wright
P2888
P304
P356
10.1038/NATURE17042
P407
P577
2016-01-01T00:00:00Z
P6179
1038585164