ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK.

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Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice.

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Q50044223-1FB695C8-0CDB-4248-A9D3-F2BBC06DBF49

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ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK.

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2017 nî lūn-bûn

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ADA-07 Suppresses Solar Ultrav ...... s by Directly Inhibiting TOPK.

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ADA-07 Suppresses Solar Ultrav ...... s by Directly Inhibiting TOPK.

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ADA-07 Suppresses Solar Ultrav ...... s by Directly Inhibiting TOPK.

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ADA-07 Suppresses Solar Ultrav ...... s by Directly Inhibiting TOPK.

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Ann M Bode

http://www.w3.org/2001/XMLSchema#string

Clara Curiel-Lewandrowski

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David Alberts

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Eunmiri Roh

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Ge Gao

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Hanyong Chen

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Joohyun Ryu

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Kanamata Reddy

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Ke Yao

http://www.w3.org/2001/XMLSchema#string

Keke Wang

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PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21

A comprehensive catalogue of somatic mutations from a human cancer genome

Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells

T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

The molecular pathways of ultraviolet-induced carcinogenesis.

Photocarcinogenesis: UVA vs UVB.

UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer.

T-LAK cell-originated protein kinase (TOPK) phosphorylation of Prx1 at Ser-32 prevents UVB-induced apoptosis in RPMI7951 melanoma cells through the regulation of Prx1 peroxidase activity.

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scholarly article

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10.1158/1535-7163.MCT-17-0212

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2017-06-27T00:00:00Z

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28655782

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5587387

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ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK.

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ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK.

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