Transcription control by the ENL YEATS domain in acute leukaemia - Wikidata - wikimedia - TriplyDB

Transcription control by the ENL YEATS domain in acute leukaemia

Transcription control by the ENL YEATS domain in acute leukaemia

http://www.wikidata.org/entity/Q38714675

about

Transcriptome modeling and phenotypic assays for cancer precision medicine.Small molecules and their role in effective preclinical target validation.Targeted Protein Degradation: from Chemical Biology to Drug Discovery.MELK is not necessary for the proliferation of basal-like breast cancer cells.Pharmacologic Targeting of Chromatin Modulators As Therapeutics of Acute Myeloid Leukemia Cancer epigenetics: Reading the future of leukaemia.YY1 Is a Structural Regulator of Enhancer-Promoter Loops.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules.Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ.Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia.Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.Chromatin dependencies in cancer and inflammation.ENLightening YEATS in antagonizing polycomb repression.Epigenetics: Addicted to reading.re-TAMD: exploring interactions between H3 peptide and YEATS domain using enhanced sampling.Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia.Targeted genome editing in acute lymphoblastic leukemia: a review Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

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P2860

Transcription control by the ENL YEATS domain in acute leukaemia

http://www.wikidata.org/entity/Q38714675

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2017 nî lūn-bûn

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2017年论文

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name

Transcription control by the ENL YEATS domain in acute leukaemia

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type

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Transcription control by the ENL YEATS domain in acute leukaemia

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prefLabel

Transcription control by the ENL YEATS domain in acute leukaemia

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Transcription control by the ENL YEATS domain in acute leukaemia

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Amanda Souza

http://www.w3.org/2001/XMLSchema#string

Bin E Li

http://www.w3.org/2001/XMLSchema#string

Dennis L Buckley

http://www.w3.org/2001/XMLSchema#string

Feng Zhang

http://www.w3.org/2001/XMLSchema#string

Georg E Winter

http://www.w3.org/2001/XMLSchema#string

Huafeng Xie

http://www.w3.org/2001/XMLSchema#string

Hyuk-Soo Seo

http://www.w3.org/2001/XMLSchema#string

James E Bradner

http://www.w3.org/2001/XMLSchema#string

Joshiawa Paulk

http://www.w3.org/2001/XMLSchema#string

Justin M Roberts

http://www.w3.org/2001/XMLSchema#string

P2860

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription

ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

hDOT1L links histone methylation to leukemogenesis.

A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Controlling the elongation phase of transcription with P-TEFb

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation

MLL translocations, histone modifications and leukaemia stem-cell development

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270-274

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