Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Advances in therapeutic targeting of the DNA damage response in cancer.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Angela Brieger

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Anne Ackermann

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Annika Graband

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Guido Plotz

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Inga Hinrichsen

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Natalie Filmann

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Tonja Düding

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P2860

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

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Modulation of error-prone double-strand break repair in mammalian chromosomes by DNA mismatch repair protein Mlh1

Mlh1 mediates tissue-specific regulation of mitotic recombination

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Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer.

DNA-PK-A candidate driver of hepatocarcinogenesis and tissue biomarker that predicts response to treatment and survival.

Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer.

Mismatch repair proteins: key regulators of genetic recombination.

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1816-1824

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scholarly article

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10.1002/MC.22640

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Stefan Zeuzem

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2017-02-22T00:00:00Z

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28224663

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.

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