Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells.
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Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponseMicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.Involvement of hyaluronan in regulation of fibroblast phenotype.In vivo evidence for the role of CD44s in promoting breast cancer metastasis to the liver.Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing.Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes.Extracellular processing of the cartilage proteoglycan aggregate and its effect on CD44-mediated internalization of hyaluronanThe extracellular matrix: an active or passive player in fibrosis?Therapeutic potential of TGF-beta inhibition in chronic renal failure.CD44 engagement promotes matrix-derived survival through the CD44-SRC-integrin axis in lipid raftsHyaluronan and hyaluronidase in genitourinary tumors.Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation.High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium.Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane.Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation.The myofibroblast matrix: implications for tissue repair and fibrosis.Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.CD44 in hematological neoplasias.Fibroblasts and myofibroblasts in renal fibrosis.CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches.Provisional matrix: A role for versican and hyaluronan.Prognostic significance of Notch signalling molecules and their involvement in the invasiveness of endometrial carcinoma cells.Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling.Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin.Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype.Probing the infiltrating character of brain tumors: inhibition of RhoA/ROK-mediated CD44 cell surface shedding from glioma cells by the green tea catechin EGCg.Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling.Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.Regulation of valvular interstitial cell phenotype and function by hyaluronic acid in 2-D and 3-D culture environmentsThe pericellular hyaluronan of articular chondrocytes.Kidney Expression of RhoA, TGF-β1, and Fibronectin in Human IgA Nephropathy
P2860
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P2860
Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hyaluronan attenuates transfor ...... imal tubular epithelial cells.
@en
type
label
Hyaluronan attenuates transfor ...... imal tubular epithelial cells.
@en
prefLabel
Hyaluronan attenuates transfor ...... imal tubular epithelial cells.
@en
P2093
P2860
P1476
Hyaluronan attenuates transfor ...... ximal tubular epithelial cells
@en
P2093
Aled O Phillips
John D Williams
Takafumi Ito
P2860
P304
P356
10.1016/S0002-9440(10)63758-3
P407
P577
2004-06-01T00:00:00Z