An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.
about
Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition.Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma.Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.New somatic BRAF splicing mutation in Langerhans cell histiocytosis.PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors.New perspectives for targeting RAF kinase in human cancer.Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.Response and Resistance to Paradox-Breaking BRAF Inhibitor in Melanomas In Vivo and Ex Vivo.
P2860
Q38702202-49C79D5E-E7F3-4AC5-B2B7-1972949A93BCQ38781872-4916506D-61F3-40E7-9EA6-B8E0AAECB47AQ40092107-2F6744A7-166C-437A-B108-E792B62B10EEQ42331849-72E24E8A-8BD5-4245-8E6D-7252E2F2D7A2Q47142625-DAA79FD4-A3E8-4856-893B-B43B5447F14DQ47688064-3DE7A92D-0ED7-4070-B82E-10F9F4202644Q48348507-A39878D2-92F1-4874-97F5-737F89CDE96DQ50042449-6CC65D00-091F-4019-9B27-E6D1994BC7E7
P2860
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
An Integrated Model of RAF Inh ...... inst Oncogenic BRAF Signaling.
@en
type
label
An Integrated Model of RAF Inh ...... inst Oncogenic BRAF Signaling.
@en
prefLabel
An Integrated Model of RAF Inh ...... inst Oncogenic BRAF Signaling.
@en
P2093
P2860
P50
P1433
P1476
An Integrated Model of RAF Inh ...... inst Oncogenic BRAF Signaling.
@en
P2093
Amaia Lujambio
Chao Zhang
Evripidis Gavathiotis
James A Fagin
Julien Bollard
Poulikos I Poulikakos
Qisheng Xin
Tamer A Ahmed
P2860
P304
P356
10.1016/J.CCELL.2016.06.024
P577
2016-07-28T00:00:00Z