αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
about
Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification.Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.Antitumor effects of radionuclide treatment using α-emitting meta-211At-astato-benzylguanidine in a PC12 pheochromocytoma model.High expression of integrin αvβ3 enables uptake of targeted fluorescent probes into ovarian cancer cells and tumors.Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.Integrated treatment using intraperitoneal radioimmunotherapy and positron emission tomography-guided surgery with 64Cu-labeled cetuximab to treat early- and late-phase peritoneal dissemination in human gastrointestinal cancer xenografts.Copper-64: a real theranostic agent
P2860
Q33703084-27B9BF7C-B89F-4CF1-BD12-95EC926EF735Q42801541-286EF032-2935-448A-8235-BA0C78A0C9D8Q47557128-9304D0C2-FF5D-4B32-8B07-23CD01CCDE27Q52651546-648F36B1-9276-45BA-AA36-871FA2C87914Q55442958-26DB7AC5-2D1F-41E0-AA78-EC346176FC48Q55508871-55EAFFC6-8D1D-495D-A886-015F3971BB4DQ57484995-27DAA828-9FB2-4889-9AF5-0716D60FB67B
P2860
αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
@en
type
label
αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
@en
prefLabel
αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
@en
P2093
P50
P1476
αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
@en
P2093
Kazunori Kawamura
Ming-Rong Zhang
Mélissa Degardin
Takako Furukawa
Tomoteru Yamasaki
Tsuneo Saga
Yasuhisa Fujibayashi
Zhao-Hui Jin
P304
P356
10.1158/1535-7163.MCT-16-0040
P577
2016-07-15T00:00:00Z