Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity
about
The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificityA novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T and B cell acute lymphoblastic leukemias in vivo.
P2860
Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Design and Characterization of ...... inished l-Glutaminase Activity
@en
type
label
Design and Characterization of ...... inished l-Glutaminase Activity
@en
prefLabel
Design and Characterization of ...... inished l-Glutaminase Activity
@en
P2093
P2860
P356
P1476
Design and Characterization of ...... inished l-Glutaminase Activity
@en
P2093
Arnon Lavie
Hien Anh Nguyen
P2860
P304
17664-17676
P356
10.1074/JBC.M116.728485
P407
P577
2016-06-27T00:00:00Z