Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells.
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Emerging data on androgen receptor splice variants in prostate cancerHSP90 inhibitors potentiate PGF2α-induced IL-6 synthesis via p38 MAP kinase in osteoblasts.Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells.Drug discovery in advanced prostate cancer: translating biology into therapy.RNA splicing and splicing regulator changes in prostate cancer pathologyAnalytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer.Targeting Androgen Receptor Aberrations in Castration-Resistant Prostate Cancer.Targeting the androgen receptor in triple-negative breast cancer: current perspectives.Clinical relevance of androgen receptor alterations in prostate cancer.Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer.Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay.Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.Clinical Evaluation and Biomarker Profiling of Hsp90 Inhibitors.A Workflow Guide to RNA-seq Analysis of Chaperone Function and Beyond.MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma.Delivery of HSP90 Inhibitor Using Water Soluble Polymeric Conjugates with High Drug Payload.Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development.Adaptive pathways and emerging strategies overcoming treatment resistance in castration resistant prostate cancer.Targeting Splicing in Prostate Cancer.Precision medicine applications in prostate cancer.
P2860
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P2860
Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Second-Generation HSP90 Inhibi ...... nt 7 in Prostate Cancer Cells.
@en
type
label
Second-Generation HSP90 Inhibi ...... nt 7 in Prostate Cancer Cells.
@en
prefLabel
Second-Generation HSP90 Inhibi ...... nt 7 in Prostate Cancer Cells.
@en
P2093
P2860
P50
P1433
P1476
Second-Generation HSP90 Inhibi ...... ant 7 in Prostate Cancer Cells
@en
P2093
Daniel Nava Rodrigues
George Seed
Gerhardt Attard
Hannah Wang
Ines Figueiredo
Johann S de Bono
John F Lyons
Nicola Wallis
Paul Workman
Roberta Ferraldeschi
P2860
P304
P356
10.1158/0008-5472.CAN-15-2186
P407
P577
2016-05-01T00:00:00Z