2-Aminoxazole and 2-Aminothiazole Dasatinib Derivatives as Potent Inhibitors of Chronic Myeloid Leukemia K562 Cells.

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2-Aminoxazole and 2-Aminothiazole Dasatinib Derivatives as Potent Inhibitors of Chronic Myeloid Leukemia K562 Cells.

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2016 nî lūn-bûn

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2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

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2016年论文

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name

2-Aminoxazole and 2-Aminothiaz ...... c Myeloid Leukemia K562 Cells.

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type

Item

label

2-Aminoxazole and 2-Aminothiaz ...... c Myeloid Leukemia K562 Cells.

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prefLabel

2-Aminoxazole and 2-Aminothiaz ...... c Myeloid Leukemia K562 Cells.

@en

P1476

2-Aminoxazole and 2-Aminothiaz ...... c Myeloid Leukemia K562 Cells.

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P2093

Mian-Tian Yang

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Xing-Xing Chai

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Ying Zhou

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Ying-Jun Fu

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Yuan-Zhen Xiong

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Zhi-Ping Cai

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P2860

Charting the molecular network of the drug target Bcr-Abl

Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.

2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (d

The development of dasatinib as a treatment for chronic myeloid leukemia (CML): from initial studies to application in newly diagnosed patients.

Synthesis and identification of a new class of antileukemic agents containing 2-(arylcarboxamide)-(S)-6-amino-4,5,6,7-tetrahydrobenzo[d]thiazole.

Dasatinib inhibits proinflammatory functions of mature human neutrophils

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

ONIOM DFT/PM3 calculation on the interaction between STI-571 and abelson tyrosine kinase.

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523-531

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scholarly article

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10.1002/ARDP.201600010

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349

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2016-05-18T00:00:00Z

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27188682

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P921

chronic myeloid leukemia