Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists.
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Total internal reflection fluorescence quantification of receptor pharmacologyGPR35 activation reduces Ca2+ transients and contributes to the kynurenic acid-dependent reduction of synaptic activity at CA3-CA1 synapsesLabel-free phenotypic profiling identified D-luciferin as a GPR35 agonistLabel-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35Label-free drug discovery.Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tanguticaApproaches for probing allosteric interactions at 7 transmembrane spanning receptors.Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery.G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease.Compound annotation with real time cellular activity profiles to improve drug discovery.Chemical genomic analysis of GPR35 signaling.PTEN deletion potentiates invasion of colorectal cancer spheroidal cells through 3D Matrigel.Label-Free Cell Phenotypic Identification of D-Luciferin as an Agonist for GPR35.Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists.Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues.Multiple tyrosine metabolites are GPR35 agonists.The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists.Aspirin metabolites are GPR35 agonists.
P2860
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P2860
Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Discovery of 2-(4-methylfuran- ...... receptor 35 (GPR35) agonists.
@en
type
label
Discovery of 2-(4-methylfuran- ...... receptor 35 (GPR35) agonists.
@en
prefLabel
Discovery of 2-(4-methylfuran- ...... receptor 35 (GPR35) agonists.
@en
P2093
P2860
P356
P1476
Discovery of 2-(4-methylfuran- ...... receptor 35 (GPR35) agonists.
@en
P2093
Ann M Ferrie
Huayun Deng
Mingqian He
Weijun Niu
P2860
P304
P356
10.1021/JM200999F
P407
P50
P577
2011-10-04T00:00:00Z