The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

http://www.wikidata.org/entity/Q38779167

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NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Inflammasomes as therapeutic targets for Alzheimer's disease.Role of neuroinflammation in neurodegeneration: new insights Inflammasomes in Inflammation-Induced Cancer.Inflammasomes link vascular disease with neuroinflammation and brain disorders.NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease.Terminal complexes of the complement system: new structural insights and their relevance to function.Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease.Cytokines and Cytokine Receptors Involved in the Pathogenesis of Alzheimer's Disease.What do we know about the inflammasome in humans?The function of NOD-like receptors in central nervous system diseases.Personalized genetics of the cholinergic blockade of neuroinflammation.The IL-1β phenomena in neuroinflammatory diseases.Beyond infection - Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders.Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation.NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury.Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury.Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists.Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion.Immune and Imaging Correlates of Mild Cognitive Impairment Conversion to Alzheimer's Disease.Neuroinflammatory responses in Alzheimer's disease.The role of astrocytes in amyloid production and Alzheimer's disease.Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts.Unconjugated bilirubin induces pyroptosis in cultured rat cortical astrocytes.Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer's Disease Brain.NLR-Dependent Regulation of Inflammation in Multiple Sclerosis- Dependent Regulation of Inflammation in Multiple Sclerosis.Microglia and CNS Interleukin-1: Beyond Immunological Concepts.TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse.Dexmedetomidine inhibits inflammation in microglia cells under stimulation of LPS and ATP by c-Fos/NLRP3/caspase-1 cascades.Role of Inflammasomes in Neuroimmune and Neurodegenerative Diseases: A Systematic Review.Modulation of the ATP-Binding Cassette B1 Transporter by Neuro-Inflammatory Cytokines: Role in the Pathogenesis of Alzheimer's Disease.Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β-stimulated murine astrocytes The Gut-Brain Axis in Alzheimer's Disease and Omega-3. A Critical Overview of Clinical Trials Anti-inflammatory Effects of Homotaurine in Patients With Amnestic Mild Cognitive Impairment

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P2860

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

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2016 nî lūn-bûn

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

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The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

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The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

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Molecular Neurodegeneration

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The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease

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Elena Calabrese

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Mario Clerici

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Martina Zoppis

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Raffaello Nemni

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Veronica Rainone

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P2860

Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells

The inflammasomes

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

“Mini-mental state”

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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s13024-016-0088-1

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scholarly article

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10.1186/S13024-016-0088-1

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11

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Roberta Mancuso

Francesca la Rosa

Federica Piancone

Ivana Marventano

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2016-03-03T00:00:00Z

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297591996

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1038380539

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26939933

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Alzheimer's disease

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