Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities

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Identification of novel small molecules that inhibit STAT3-dependent transcription and function.Pharmacologic inhibition of STAT5 in acute myeloid leukemia.

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P2860

Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities

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http://www.wikidata.org/entity/Q38782370

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

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Disarming an Electrophilic War ...... ng Pharmacokinetic Liabilities

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type

Item

label

Disarming an Electrophilic War ...... ng Pharmacokinetic Liabilities

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prefLabel

Disarming an Electrophilic War ...... ng Pharmacokinetic Liabilities

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P1476

Disarming an Electrophilic War ...... ng Pharmacokinetic Liabilities

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P2093

Ami B Patel

http://www.w3.org/2001/XMLSchema#string

Andrew E Shouksmith

http://www.w3.org/2001/XMLSchema#string

Dan P Ball

http://www.w3.org/2001/XMLSchema#string

David A Rosa

http://www.w3.org/2001/XMLSchema#string

Elvin D de Araujo

http://www.w3.org/2001/XMLSchema#string

Ji Sung Park

http://www.w3.org/2001/XMLSchema#string

Michael W Deininger

http://www.w3.org/2001/XMLSchema#string

Nadeem A Vellore

http://www.w3.org/2001/XMLSchema#string

Patrick T Gunning

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Ping-Shan Lai

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P2860

An enzyme from rat liver catalysing conjugations with glutathione

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

P304

850-861

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scholarly article

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10.1002/CMDC.201600021

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Ahmed M. Ali

Anna M Eiring

P577

2016-03-30T00:00:00Z

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27028877

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4963206

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Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities

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P2860

P2860

Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities

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P1433

P1476

P2093

P2860

P304

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P356

P433

P478

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P698

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P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932