Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. - Wikidata - wikimedia - TriplyDB

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

http://www.wikidata.org/entity/Q38785882

about

Hepatitis B: progress in understanding chronicity, the innate immune response, and cccDNA protection Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex Genome-wide identification of direct HBx genomic targets Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts.The Role of cccDNA in HBV Maintenance.Proteomic profiling of HBV infected liver biopsies with different fibrotic stages.The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection.DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms.Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication.Hepatitis B Virus Protein X Induces Degradation of Talin-1.Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs.LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity.Evolving New Strategies for the Medical Management of Chronic Hepatitis B Virus Infection.Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.HBV DNA Integration: Molecular Mechanisms and Clinical Implications HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis.Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants The current status and future directions of hepatitis B antiviral drug discovery.Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.Novel targets for hepatitis B virus therapy.Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6.A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation-and Beyond?Viral hepatitis and liver cancer.Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication.Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B.Recombinant cccDNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model.New Direct-Acting Antiviral Agents and Immunomodulators for Hepatitis B Virus Infection.[Personalized treatment of viral hepatitis of the present and the future : Hepatitis B, C, delta, and E].HBx-elevated MSL2 Modulates HBV cccDNA through Inducing Degradation of APOBEC3B to Enhance Hepatocarcinogenesis.Inducible Rubicon facilitates viral replication by antagonizing interferon production.Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction.4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy.[A new restriction factor against HBV infection: the SMC5/6 complex].The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state.Virology: The X-Files of hepatitis B.Hepatitis B cure: From discovery to regulatory approval.The Structural Biology of Hepatitis B Virus: Form and Function.Hepatitis B virus X protein crosses out Smc5/6 complex to maintain covalently closed circular DNA transcription.Hepatitis B Virus and DNA Damage Response: Interactions and Consequences for the Infection.

P2860

Q28069273-C059E1CD-EC7A-48CA-9A9A-5DE07B780156 Q28554481-E971CB88-3461-4C1A-9BDB-447F7ECD845E Q29048191-A9CC38C9-72EE-49F2-BCBE-34AA09C4AC62 Q30854409-46A2DD32-B346-40A1-9F33-02BE07E648D6 Q32182914-E3A3E73A-D6FF-424A-8786-730290416D60 Q33587550-537ADEDB-A35B-47C0-ABB8-5E7C991C45CC Q36251481-0C7527B5-D2FD-435C-B429-CCA0473B9341 Q37307061-8F29D58D-6CAB-4C5D-9328-A3B81732AE49 Q37347289-102C2281-7B0D-4EBF-9772-6957050FB779 Q37364333-171D5C28-5383-4F58-B2BF-494320D611F4 Q37378812-939CBBEB-9E00-4337-9C66-E20AE85DD69F Q37397410-A38318B6-F530-42F2-921B-0D88E52738D0 Q37421909-D473BA3B-60B5-41EF-B0CD-F4D06F03F8BB Q37540212-4C38C4C1-1B84-40D9-8D94-82CC7E875761 Q38721357-F967396E-2F3C-46B9-8E31-F6D979C7CA20 Q38732528-0DD68743-3831-4AEC-B2E0-35F84838134B Q38744233-6FDE8939-B446-4BEB-8134-5F6C01E65DC0 Q38755680-F04F8046-E455-4B33-9D5A-FDA0642FC58B Q38802098-62D62F41-79B2-47DC-A4C7-577E9C9ECC50 Q39006737-B68C600C-FF09-46C8-A1C7-D0477974D662 Q39067316-79992057-DD15-4A15-B767-FED1F649B932 Q39214968-02DB88AC-C1F2-49C1-A378-E3B6AABFBA58 Q39322379-E1064218-34D8-4056-8E79-C7770E0A23BC Q40046596-2C85A93E-C495-49F2-8166-4D78EFABF97B Q40051813-BBC7736B-FE91-4B3B-BE3D-56B0A0C28698 Q40073818-87EA1B61-ED53-442C-8D6E-D8C970D84E52 Q40106034-53774428-0316-45AA-8532-3AA2BF86CE76 Q40130098-A17E4211-67C9-4D07-A12B-FA22C5DBCAA2 Q40153413-D7317051-B5EE-443D-8B96-87E1CBA86E56 Q40162017-E7E2CCFD-8EEE-4EC6-B0EA-B9F443023B5A Q40251263-BD928A77-225E-43E7-A935-6BE81710660C Q40303257-354CE067-5720-48BE-A683-463694C40834 Q40470227-20B45041-291C-4758-8F7E-97B88086E8C7 Q40498729-5493A11D-13CE-43DE-9F1C-5541E2DAA645 Q40676461-1EB780C0-AA28-401E-B892-49187A08EDBB Q40850304-99975ADD-F161-4818-8017-E4D824304984 Q41952398-87983296-3ED3-45F3-A28D-99001283D11D Q42048428-008FF586-D3D6-4059-B865-4D8FEB4346A4 Q44523193-D2A45A45-F972-4A83-B28C-5906EF46753E Q45326057-04FEA38A-3651-457F-BE7A-A59E0057FA1F

P2860

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

http://www.wikidata.org/entity/Q38785882

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

@en

type

label

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

@en

prefLabel

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.

@en

P1433

Q38785882-74AFAF6C-8D5A-467A-9AAF-CFD2DAC36ACB

P1476

Q38785882-3141E2E5-1C57-4F3A-B55E-6E13BC3F4905

P2093

Q38785882-15DEA2A2-6FFA-4811-ADB6-12A4AE9E6880

Q38785882-1B2DF55D-5473-4479-8807-CAF44ADF627D

Q38785882-3A5A57B1-0732-4515-807E-DB1D09606BD4

Q38785882-5A6AA5F7-9FD1-4F05-BFC7-15FE563B367D

Q38785882-752DF5FD-48E2-4F57-8F30-4B164929D903

Q38785882-84AE0B71-BCDD-4B5B-971C-9D6580AA5563

Q38785882-93E66249-102B-46AF-A6EB-467F08E076A0

Q38785882-C17B5000-D429-4CF9-B8BD-AB75265B6DD0

Q38785882-D83CCED2-D486-471B-B976-DCEFD4D6D139

Q38785882-E1260BC4-501D-48CA-968C-AF8C68AA832C

P2860

Q38785882-047E2826-23A8-4EA2-823D-6302832F0B9B

Q38785882-07E0CF13-A19F-4B2B-A069-7FFAA775C996

Q38785882-0D3B0044-7F5A-4E88-93E3-22459B14D0FE

Q38785882-1580752F-66BF-4BE4-8681-37376B7FA60C

Q38785882-175EB1B9-03F0-46E4-B9FE-2A677A702485

Q38785882-1864ADA9-C665-429B-97C2-5C9D53E18A62

Q38785882-1A7DB05A-7AE9-4123-96DA-8E121E729729

Q38785882-1CCEC63A-ABB6-4859-8B28-BBC1353D6EC1

Q38785882-1DFF3DF7-56D6-487C-A1AA-49D8F1DAB676

Q38785882-28ECC6C8-1159-44FA-BFA2-686C2F720971

P2888

Q38785882-EE0F8A51-E7D9-483D-8FAA-71CEAFFCB3C1

P304

Q38785882-4AF0356C-0A94-428D-AF85-BD814AC64322

P31

Q38785882-8092A2E8-3069-49B5-820C-E34E709B84F9

P356

Q38785882-59E77F6C-70A8-4092-AA9B-1A1F7BFE9C91

P407

Q38785882-0038F4F5-364B-4968-80DE-46FE3965E885

P433

Q38785882-833DF4D1-5953-4811-9343-1548D3923DA8

P478

Q38785882-D580C46B-BB15-4699-A974-8AF7F5F7A29C

P50

Q38785882-90257BBA-2714-4C0D-96DA-905AFAD39C91

P577

Q38785882-A6971AB1-8BB7-48CE-8ED5-46E64C0DEBEE

P6179

Q38785882-C9EFC624-9562-48A2-9763-71B9C0A70087

P698

Q38785882-89E8584F-DE6D-4CFE-BBFE-C73ECF1C4B16

P356

P1433

P1476

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

@en

P2093

Adrien Decorsière

http://www.w3.org/2001/XMLSchema#string

Christine M Livingston

http://www.w3.org/2001/XMLSchema#string

Congrong Niu

http://www.w3.org/2001/XMLSchema#string

Fabien Abdul

http://www.w3.org/2001/XMLSchema#string

Henrik Mueller

http://www.w3.org/2001/XMLSchema#string

Michel Strubin

http://www.w3.org/2001/XMLSchema#string

Olivier Hantz

http://www.w3.org/2001/XMLSchema#string

Pieter C van Breugel

http://www.w3.org/2001/XMLSchema#string

Rudolf K Beran

http://www.w3.org/2001/XMLSchema#string

Simon P Fletcher

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex

Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription

A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery

Hepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activities

Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2

P2888

P304

386-389

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE17170

http://www.w3.org/2001/XMLSchema#string

P407

P433

7594

http://www.w3.org/2001/XMLSchema#string

P478

531

http://www.w3.org/2001/XMLSchema#string

P50

Laetitia Gerossier

P577

2016-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1046028879

http://www.w3.org/2001/XMLSchema#string

P698

26983541

http://www.w3.org/2001/XMLSchema#string