Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest. - Wikidata - wikimedia - TriplyDB

Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

http://www.wikidata.org/entity/Q38789815

about

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint.Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.Using Human iPSC-Derived Neurons to Uncover Activity-Dependent Non-Coding RNAs.Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.Preserving Salivary Gland Physiology against Genotoxic Damage - The Tousled Way.Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer.De Novo and Inherited Loss-of-Function Variants in TLK2: Clinical and Genotype-Phenotype Evaluation of a Distinct Neurodevelopmental Disorder.Molecular basis of Tousled-Like Kinase 2 activation.A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

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P2860

Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

http://www.wikidata.org/entity/Q38789815

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

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Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

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Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

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Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

@en

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Melinda Aprelia

http://www.w3.org/2001/XMLSchema#string

Wytse Bruinsma

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P2860

Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication

Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

Multiplex genome engineering using CRISPR/Cas systems

CBP/p300-mediated acetylation of histone H3 on lysine 56

Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis

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659-670

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scholarly article

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10.15252/EMBR.201540767

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5

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17

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René H. Medema

Jeroen van den Berg

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2016-03-01T00:00:00Z

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296632124

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