Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition.
about
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndromeThe Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia.Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence.Ibrutinib inhibits pre-BCR+ B-cell acute lymphoblastic leukemia progression by targeting BTK and BLK.E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia.Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.Tonic B-cell receptor signaling in diffuse large B-cell lymphoma.Fine tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation.High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia.EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia.New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update.
P2860
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P2860
Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Pre-BCR signaling in precursor ...... be targeted by SYK inhibition.
@en
type
label
Pre-BCR signaling in precursor ...... be targeted by SYK inhibition.
@en
prefLabel
Pre-BCR signaling in precursor ...... be targeted by SYK inhibition.
@en
P2093
P2860
P356
P1433
P1476
Pre-BCR signaling in precursor ...... be targeted by SYK inhibition.
@en
P2093
D A Thomas
E Ten Hacken
F Seyfried
G P Coffey
H Kantarjian
J A Burger
P2860
P2888
P304
P356
10.1038/LEU.2016.9
P577
2016-02-05T00:00:00Z
P6179
1053594962