Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.

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Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

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2015年论文

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name

Phenylhydrazones as Correctors ...... embrane Conductance Regulator.

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Phenylhydrazones as Correctors ...... embrane Conductance Regulator.

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prefLabel

Phenylhydrazones as Correctors ...... embrane Conductance Regulator.

@en

P1476

Phenylhydrazones as Correctors ...... membrane Conductance Regulator

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P2093

Benedetta Pollarolo

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Erika Nieddu

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Marco T Mazzei

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Maria Anzaldi

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Mauro Mazzei

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Silvia Schenone

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P2860

UCSF Chimera--a visualization system for exploratory research and analysis

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Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles.

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain.

Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1.

Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.

Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.

P304

112-123

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P31

scholarly article

P356

10.1002/ARDP.201500352

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P433

http://www.w3.org/2001/XMLSchema#string

P478

349

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P50

Nicoletta Pedemonte

Luis Galietta

P577

2015-12-23T00:00:00Z

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P698

26701662

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P921

cystic fibrosis

transmembrane protein