Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas. - Wikidata - wikimedia - TriplyDB

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

http://www.wikidata.org/entity/Q38813736

about

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth GBM-associated mutations and altered protein expression are more common in young patients.Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation.Pleiotrophin is a driver of vascular abnormalization in glioblastoma.Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma.Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease.A Chimeric Antibody against ACKR3/CXCR7 in Combination with TMZ Activates Immune Responses and Extends Survival in Mouse GBM Models.CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis.

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Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

http://www.wikidata.org/entity/Q38813736

description

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SCISIGNAL.AAA1690

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Science Signaling

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Pleiotrophin promotes vascular ...... in patients with astrocytomas.

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Anja Smits

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Anna Dimberg

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Anna-Karin Olsson

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Chuan Jin

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Di Yu

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Karin Forsberg Nilsson

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Lei Zhang

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Liisi Laaniste

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Magnus Essand

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Peetra U Magnusson

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P2860

Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

IDH1 and IDH2 mutations in gliomas

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis.

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

A role for receptor tyrosine phosphatase zeta in glioma cell migration

Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth

Midkine and pleiotrophin: two related proteins involved in development, survival, inflammation and tumorigenesis

Differential induction of glioblastoma migration and growth by two forms of pleiotrophin

The somatic genomic landscape of glioblastoma

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406

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8

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K Elisabet Ohlin Sjöström

Lothar C Dieterich

Fredrik Pontén

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26645582

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