Effects of diadenosine polyphosphates (Ap(n)As) and adenosine polyphospho guanosines (Ap(n)Gs) on rat mesenteric artery P2X receptor ion channels.
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The critical role of adenosine and guanosine in the affinity of dinucleoside polyphosphates to P(2X)-receptors in the isolated perfused rat kidneyStructure-activity relationships of diadenosine polyphosphates (Ap(n)As), adenosine polyphospho guanosines (Ap(n)Gs) and guanosine polyphospho guanosines (Gp(n)Gs) at P2 receptors in the rat mesenteric arterial bedDisruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstrictionActivation and regulation of purinergic P2X receptor channelsEmerging roles for P2X1 receptors in platelet activation.Purinergic receptors expressed in human skeletal muscle fibresUridine adenosine tetraphosphate induces contraction and relaxation in rat aorta.Structural interpretation of P2X receptor mutagenesis studies on drug actionThe P2X1 receptor and platelet function.Mechanistic insights from resolving ligand-dependent kinetics of conformational changes at ATP-gated P2X1R ion channels.ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets.Lack of run-down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels.Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.Uridine adenosine tetraphosphate affects contractility of mouse aorta and decreases blood pressure in conscious rats and mice.ATP binding at human P2X1 receptors. Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists.Diadenosine pentaphosphate modulates glomerular arteriolar tone and glomerular filtration rate.Diadenosine tetra- and pentaphosphates affect contractility and bioelectrical activity in the rat heart via P2 purinergic receptors.
P2860
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P2860
Effects of diadenosine polyphosphates (Ap(n)As) and adenosine polyphospho guanosines (Ap(n)Gs) on rat mesenteric artery P2X receptor ion channels.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Effects of diadenosine polypho ...... ery P2X receptor ion channels.
@en
type
label
Effects of diadenosine polypho ...... ery P2X receptor ion channels.
@en
prefLabel
Effects of diadenosine polypho ...... ery P2X receptor ion channels.
@en
P2093
P2860
P356
P1476
Effects of diadenosine polypho ...... ery P2X receptor ion channels.
@en
P2093
D P Gitterman
H Schlüter
P2860
P304
P356
10.1038/SJ.BJP.0702993
P407
P577
2000-01-01T00:00:00Z