Designing helical peptide inhibitors of protein-protein interactions
about
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1Peptides and peptidomimetics as regulators of protein-protein interactions.Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.A precisely positioned chiral center in an i, i + 7 tether modulates the helicity of the backbone peptide.Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site.coiled-coil peptides as scaffolds for disrupting protein-protein interactions
P2860
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P2860
Designing helical peptide inhibitors of protein-protein interactions
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Designing helical peptide inhibitors of protein-protein interactions
@en
type
label
Designing helical peptide inhibitors of protein-protein interactions
@en
prefLabel
Designing helical peptide inhibitors of protein-protein interactions
@en
P2860
P1476
Designing helical peptide inhibitors of protein-protein interactions
@en
P2093
Raheleh Rezaei Araghi
P2860
P356
10.1016/J.SBI.2016.04.001
P577
2016-04-25T00:00:00Z