c-Met-mediated reactivation of PI3K/AKT signaling contributes to insensitivity of BRAF(V600E) mutant thyroid cancer to BRAF inhibition.

c-Met-mediated reactivation of PI3K/AKT signaling contributes to insensitivity of BRAF(V600E) mutant thyroid cancer to BRAF inhibition.

Item
http://www.wikidata.org/entity/Q38828874
Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation.P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells.Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model.Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E.Overexpression of miR-101 promotes TRAIL-induced mitochondrial apoptosis in papillary thyroid carcinoma by targeting c-met and MCL-1.Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma.Genetic mutations in accordance with a low malignant potential tumour are not demonstrated in clear cell papillary renal cell carcinoma.EGFR inhibition enhances the antitumor efficacy of a selective BRAF V600E inhibitor in thyroid cancer cell lines.The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells
P2860

c-Met-mediated reactivation of PI3K/AKT signaling contributes to insensitivity of BRAF(V600E) mutant thyroid cancer to BRAF inhibition.

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http://www.wikidata.org/entity/Q38828874
description
2015 nî lūn-bûn
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2015年の論文
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name
c-Met-mediated reactivation of ...... oid cancer to BRAF inhibition.
@en
type
label
c-Met-mediated reactivation of ...... oid cancer to BRAF inhibition.
@en
prefLabel
c-Met-mediated reactivation of ...... oid cancer to BRAF inhibition.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
c-Met-mediated reactivation of ...... roid cancer to BRAF inhibition
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698