Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition. - Wikidata - wikimedia - TriplyDB

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition.

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition.

http://www.wikidata.org/entity/Q38833154

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Cutting through the complexities of mTOR for the treatment of stroke Erythropoietin and Neonatal Neuroprotection Disorders of GABA metabolism: SSADH and GABA-transaminase deficiencies Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.Serial plasma metabolites following hypoxic-ischemic encephalopathy in a nonhuman primate model.Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse Inherited disorders of gamma-aminobutyric acid metabolism and advances in ALDH5A1 mutation identification.Regeneration in the nervous system with erythropoietin Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge-Weber Syndrome.Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism Therapeutic relevance of mTOR inhibition in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism.The Uptake of GABA in Trypanosoma cruzi.Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity mTOR inhibitors rescue premature lethality and attenuate dysregulation of GABAergic/glutamatergic transcription in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism.In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells.Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder.mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice.Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies.pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity.Aberrant mTOR signaling and disrupted autophagy: The missing link in potential vigabatrin-associated ocular toxicity?

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P2860

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition.

http://www.wikidata.org/entity/Q38833154

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Defects in GABA metabolism aff ...... alleviated by mTOR inhibition.

@en

type

label

Defects in GABA metabolism aff ...... alleviated by mTOR inhibition.

@en

prefLabel

Defects in GABA metabolism aff ...... alleviated by mTOR inhibition.

@en

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EMBO Molecular Medicine

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Defects in GABA metabolism aff ...... alleviated by mTOR inhibition.

@en

P2093

Jingjing Liu

http://www.w3.org/2001/XMLSchema#string

K Michael Gibson

http://www.w3.org/2001/XMLSchema#string

Kara R Vogel

http://www.w3.org/2001/XMLSchema#string

Ronak Lakhani

http://www.w3.org/2001/XMLSchema#string

Sarah F Burnett

http://www.w3.org/2001/XMLSchema#string

Suresh Subramani

http://www.w3.org/2001/XMLSchema#string

P2860

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Autophagy fights disease through cellular self-digestion

Expression of a glutamate decarboxylase homologue is required for normal oxidative stress tolerance in Saccharomyces cerevisiae.

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast.

GABA and GABA receptors in the central nervous system and other organs

Defining the role of mTOR in cancer

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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551-566

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10.1002/EMMM.201303356

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4

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24578415

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3992080

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