Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.
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Phosphorylation of Single Stranded RNA Virus Proteins and Potential for Novel Therapeutic StrategiesAdapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulenceAntagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus InfectionChikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies.Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling.4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression.Imipramine Inhibits Chikungunya Virus Replication in Human Skin Fibroblasts through Interference with Intracellular Cholesterol Trafficking.Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments.SNAP-tagged Chikungunya Virus Replicons Improve Visualisation of Non-Structural Protein 3 by Fluorescence Microscopy.PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target.Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins.Polyprotein Processing as a Determinant for in Vitro Activity of Semliki Forest Virus Replicase.Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes.Interactions of Alphavirus nsP3 Protein with Host Proteins.A Chikungunya virus trans-replicase system reveals the importance of delayed non-structural polyprotein processing for efficient replication complex formation in mosquito cells.The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last.Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus.Miltefosine inhibits Chikungunya virus replication in human primary dermal fibroblasts.Multiple Host Factors Interact with Hypervariable Domain of Chikungunya Virus nsP3 and Determine Viral Replication in Cell-Specific ModeThe Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies
P2860
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P2860
Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Differential Phosphatidylinosi ...... ation Complex Internalization.
@en
type
label
Differential Phosphatidylinosi ...... ation Complex Internalization.
@en
prefLabel
Differential Phosphatidylinosi ...... ation Complex Internalization.
@en
P2093
P2860
P50
P356
P1433
P1476
Differential Phosphatidylinosi ...... cation Complex Internalization
@en
P2093
Andres Merits
Margit Mutso
Roberta Biasiotto
P2860
P304
11420-11437
P356
10.1128/JVI.01579-15
P407
P50
P577
2015-09-02T00:00:00Z