Glucose promotes secretion-dependent renal cyst growth.

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P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells.

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Q37442070-B862126B-EF8E-4B9A-8E52-276C57AF4554

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Glucose promotes secretion-dependent renal cyst growth.

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Glucose promotes secretion-dependent renal cyst growth.

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Glucose promotes secretion-dependent renal cyst growth.

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Glucose promotes secretion-dependent renal cyst growth.

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P1476

Glucose promotes secretion-dependent renal cyst growth.

@en

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Andre Kraus

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Bjoern Buchholz

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Dorien J M Peters

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Gunnar Schley

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Kai-Uwe Eckardt

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Karl Kunzelmann

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Rainer Schreiber

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Ruth Stadler

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P2860

Advanced glycated end-products affect HIF-transcriptional activity in renal cells

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Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.

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Glucose stimulates calcium-activated chloride secretion in small intestinal cells.

Crosstalk between cAMP and Ca2+ signaling in non-excitable cells.

Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

The impact of type II diabetes mellitus in patients with autosomal dominant polycystic kidney disease.

Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.

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s00109-015-1337-4

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107-117

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scholarly article

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10.1007/S00109-015-1337-4

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P478

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2015-09-03T00:00:00Z

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281541545

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1011835676

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P698

26334260

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Glucose promotes secretion-dependent renal cyst growth.

about

P2860

P2860

Glucose promotes secretion-dependent renal cyst growth.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P577

P5875

P6179

P698

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P577

P5875

P6179

P698