Model-Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

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HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B Clinical responses to ERK inhibition in BRAFV600E-mutant colorectal cancer predicted using a computational model.

P2860

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Model-Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

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Model-Based Design of a Decisi ...... Genetic and Protein Biomarkers

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Model-Based Design of a Decisi ...... Genetic and Protein Biomarkers

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Model-Based Design of a Decisi ...... Genetic and Protein Biomarkers

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Model-Based Design of a Decisi ...... Genetic and Protein Biomarkers

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C F McDonagh

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D C Kirouac

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D Yarar

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J Du

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J Lahdenranta

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M D Onsum

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U B Nielsen

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P2860

Hallmarks of Cancer: The Next Generation

The Cancer Genome Atlas Pan-Cancer analysis project

Factors underlying sensitivity of cancers to small-molecule kinase inhibitors

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

EGF-ERBB signalling: towards the systems level

ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.

The quest to overcome resistance to EGFR-targeted therapies in cancer.

Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS-ERK signaling.

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scholarly article

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10.1002/PSP4.19

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2015-03-04T00:00:00Z

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280584719

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26225238

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protein design

biomarker

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Model-Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

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P2860

P2860

Model-Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P921

P932