A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response.
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MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesImmune signaling by RIG-I-like receptorsUbiquitin in the activation and attenuation of innate antiviral immunityRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsMDA5 and LGP2: accomplices and antagonists of antiviral signal transductionSingle Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signalingA non-canonical role of the p97 complex in RIG-I antiviral signalingCytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3Functional characterization of domains of IPS-1 using an inducible oligomerization system.Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein.Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFNRNA sequencing-based analysis of the spleen transcriptome following infectious bronchitis virus infection of chickens selected for different mannose-binding lectin serum concentrationsMechanisms of MAVS regulation at the mitochondrial membrane.Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6.Structural Insights into mitochondrial antiviral signaling protein (MAVS)-tumor necrosis factor receptor-associated factor 6 (TRAF6) signaling.GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosomeChlamydia pneumoniae impairs the innate immune response in infected epithelial cells by targeting TRAF3Ubiquitination in the antiviral immune responseIntracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response.HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex.TRAF molecules in cell signaling and in human diseasesUBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling.Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78.Emerging role of ubiquitination in antiviral RIG-I signalingRecognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses.Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses.Antiviral RNA recognition and assembly by RLR family innate immune sensors.How RIG-I like receptors activate MAVS.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity.IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates.Down regulation of TRIF, TLR3, and MAVS in HCV infected liver correlates with the outcome of infection.ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
P2860
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P2860
A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
A functional C-terminal TRAF3- ...... of the IFN antiviral response.
@en
type
label
A functional C-terminal TRAF3- ...... of the IFN antiviral response.
@en
prefLabel
A functional C-terminal TRAF3- ...... of the IFN antiviral response.
@en
P2093
P2860
P356
P1433
P1476
A functional C-terminal TRAF3- ...... of the IFN antiviral response.
@en
P2093
Deshanthe Joseph-Pillai
Eliane F Meurs
John Hiscott
Meztli Arguello
Myriam Vilasco
Rongtuan Lin
Steven J Werden
Thi Lien-Anh Nguyen
Tiejun Zhao
P2860
P2888
P304
P356
10.1038/CR.2011.2
P50
P577
2011-01-04T00:00:00Z