DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination
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The Epigenetic Pathways to Ribosomal DNA SilencingFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressHemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1Vitamin E Modifies High-Fat Diet-Induced Increase of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice.An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In VitroHemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine ReaderJarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.Regulation of maintenance DNA methylation via histone ubiquitylation.Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.Enzymology of Mammalian DNA Methyltransferases.Genetic Studies on Mammalian DNA Methyltransferases.Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.Zscan4 Inhibits Maintenance DNA Methylation to Facilitate Telomere Elongation in Mouse Embryonic Stem Cells.Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation.DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation.Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.RFTS-dependent negative regulation of Dnmt1 by nucleosome structure and histone tails.Target specificity of mammalian DNA methylation and demethylation machinery.An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association.Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif.Synthesis of ubiquitylated histone H3 using a thiirane linker for chemical ligation.Global delay in nascent strand DNA methylation.Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance.A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations.WDR79 mediates the proliferation of non-small cell lung cancer cells by regulating the stability of UHRF1.Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward ChromatinMethylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesionsChromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1Discerning evolutionary trends in post-translational modification and the effect of intrinsic disorder: Analysis of methylation, acetylation and ubiquitination sites in human proteins
P2860
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P2860
DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
DNA methylation requires a DNM ...... IM) and histone ubiquitination
@en
type
label
DNA methylation requires a DNM ...... IM) and histone ubiquitination
@en
prefLabel
DNA methylation requires a DNM ...... IM) and histone ubiquitination
@en
P2093
P2860
P356
P1433
P1476
DNA methylation requires a DNM ...... IM) and histone ubiquitination
@en
P2093
David Hörl
Federica La Mastra
Garwin Pichler
Hartmann Harz
Heinrich Leonhardt
Ian Marc Bonapace
Ignasi Forné
Karin Fellinger
Martha Smets
P2860
P2888
P304
P356
10.1038/CR.2015.72
P577
2015-06-12T00:00:00Z