Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD.

Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD.

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http://www.wikidata.org/entity/Q38885005
Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations.Single-molecule pull-down for investigating protein-nucleic acid interactions.Structural and functional insights into the fly microRNA biogenesis factor Loquacious.Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production.Helicases in Antiviral Immunity: Dual Properties as Sensors and Effectors.Overexpression and purification of Dicer and accessory proteins for biochemical and structural studies.The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2.Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.Viral suppressors of RNAi employ a rapid screening mode to discriminate viral RNA from cellular small RNA.Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro.Loquacious-PD facilitates Drosophila Dicer-2 cleavage through interactions with the helicase domain and dsRNA.Loquacious-PD removes phosphate inhibition of Dicer-2 processing of hairpin RNAs into siRNAs.Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects.Functional Analysis of RNA Interference-Related Soybean Pod Borer (Lepidoptera) Genes Based on Transcriptome Sequences.Biochemical Comparison of dsRNA Degrading Nucleases in Four Different Insects.
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Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD.

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http://www.wikidata.org/entity/Q38885005
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Drosophila dicer-2 cleavage is ...... re modulated by Loquacious-PD.
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label
Drosophila dicer-2 cleavage is ...... re modulated by Loquacious-PD.
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prefLabel
Drosophila dicer-2 cleavage is ...... re modulated by Loquacious-PD.
@en
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Drosophila dicer-2 cleavage is ...... re modulated by Loquacious-PD.
@en
P2093
P2860
P304
P31
P356
10.1016/J.MOLCEL.2015.03.012
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P478
P50
P577
P698
P921
P932