ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

Item
http://www.wikidata.org/entity/Q38887917
Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistanceABCG1 maintains high-grade glioma survival in vitro and in vivo.Inhibitors of protein methyltransferases as chemical tools.Therapeutic Potential and Utility of Elacridar with Respect to P-glycoprotein Inhibition: An Insight from the Published In Vitro, Preclinical and Clinical Studies.Targeting Enhancer of Zeste Homolog 2 as a promising strategy for cancer treatmentTransgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in DrosophilaSmall molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells.The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors.Epigenetic regulation in medulloblastoma.Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.Initial testing (stage 1) of tazemetostat (EPZ-6438), a novel EZH2 inhibitor, by the Pediatric Preclinical Testing Program.Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.Modulation of the ATP-Binding Cassette B1 Transporter by Neuro-Inflammatory Cytokines: Role in the Pathogenesis of Alzheimer's Disease.Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.Next-Generation Modeling of Human Cancers
P2860

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

Item
http://www.wikidata.org/entity/Q38887917
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
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name
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.
@en
type
label
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.
@en
prefLabel
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698