Rasagiline and selegiline suppress calcium efflux from mitochondria by PK11195-induced opening of mitochondrial permeability transition pore: a novel anti-apoptotic function for neuroprotection.
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Type B and A monoamine oxidase and their inhibitors regulate the gene expression of Bcl-2 and neurotrophic factors in human glioblastoma U118MG cells: different signal pathways for neuroprotection by selegiline and rasagiline.Classical and Novel TSPO Ligands for the Mitochondrial TSPO Can Modulate Nuclear Gene Expression: Implications for Mitochondrial Retrograde Signaling.3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases.Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons.Neurotrophic function of phytochemicals for neuroprotection in aging and neurodegenerative disorders: modulation of intracellular signaling and gene expression.Phytochemicals prevent mitochondrial membrane permeabilization and protect SH-SY5Y cells against apoptosis induced by PK11195, a ligand for outer membrane translocator protein.Rasagiline prevents cyclosporine A-sensitive superoxide flashes induced by PK11195, the initial signal of mitochondrial membrane permeabilization and apoptosis.
P2860
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P2860
Rasagiline and selegiline suppress calcium efflux from mitochondria by PK11195-induced opening of mitochondrial permeability transition pore: a novel anti-apoptotic function for neuroprotection.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Rasagiline and selegiline supp ...... function for neuroprotection.
@en
type
label
Rasagiline and selegiline supp ...... function for neuroprotection.
@en
prefLabel
Rasagiline and selegiline supp ...... function for neuroprotection.
@en
P2093
P2860
P1476
Rasagiline and selegiline supp ...... function for neuroprotection.
@en
P2093
Kimiko Kazumura
Makoto Naoi
Toshihiko Osawa
Wakako Maruyama
P2860
P2888
P304
P356
10.1007/S00702-015-1398-0
P577
2015-04-12T00:00:00Z