Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)
about
Pattern Recognition Receptors in Cancer Progression and MetastasisMultiple regulation pathways and pivotal biological functions of STAT3 in cancer.A STAT inhibitor patent review: progress since 2011.The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations.Novel STAT 3 inhibitors for treating gastric cancer.Cancer stem cell (CSC) inhibitors: a review of recent patents (2012-2015).Molecular and functional characterization of a new 3' end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant ImatinibMitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells.Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome.Targeting the IL-6/JAK/STAT3 signalling axis in cancer.Effects of purified Omphalia lapidescens protein on metastasis, cell cycle, apoptosis and the JAK-STAT signaling pathway in SGC-7901 human gastric cells.A First-in-Human Phase 1 Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers.Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development.
P2860
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P2860
Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
Hitting the right spot: Mechan ...... tor of Transcription 3 (STAT3)
@en
type
label
Hitting the right spot: Mechan ...... tor of Transcription 3 (STAT3)
@en
prefLabel
Hitting the right spot: Mechan ...... tor of Transcription 3 (STAT3)
@en
P2093
P2860
P50
P1433
P1476
Hitting the right spot: Mechan ...... tor of Transcription 3 (STAT3)
@en
P2093
Carlo V Catapano
Davide Genini
Erik Laurini
Giuseppina M Carbone
Jessica Merulla
Lara Brambilla
P2860
P304
P356
10.1016/J.MOLONC.2015.02.012
P577
2015-03-05T00:00:00Z