Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
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Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insultsCaspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.The journey to autism: Insights from neuroimaging studies of infants and toddlers.More alive than dead: non-apoptotic roles for caspases in neuronal development, plasticity and disease.Axon degeneration: context defines distinct pathways.Common and Divergent Mechanisms in Developmental Neuronal Remodeling and Dying Back Neurodegeneration.Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury.A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration.Physiological functions of non-apoptotic caspase activity in the nervous system.Neurodegeneration and regeneration.FOXO protects against age-progressive axonal degeneration.FOXO in Neural Cells and Diseases of the Nervous System.Remodeling of the Actin/Spectrin Membrane-associated Periodic Skeleton, Growth Cone Collapse and F-Actin Decrease during Axonal Degeneration.EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans.Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury.
P2860
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P2860
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
@en
type
label
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
@en
prefLabel
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
@en
P2093
P2860
P1433
P1476
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling
@en
P2093
David J Simon
Henrik Molina
Jason Pitts
Marc Tessier-Lavigne
Milica Tešić Mark
Olav Olsen
Yuya Yamagishi
P2860
P304
P356
10.1016/J.CELL.2016.01.032
P407
P577
2016-02-18T00:00:00Z