Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling.
about
Adhesion protein networks reveal functions proximal and distal to cell-matrix contactsβ1 Integrins as Therapeutic Targets to Disrupt Hallmarks of CancerIntegrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.The integrin adhesome network at a glancePhosphoproteome Analysis Reveals Phosphorylation Underpinnings in the Brains of Nurse and Forager Honeybees (Apis mellifera)PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassemblyHighly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal AdhesionsModulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition.Integrin endosomal signalling suppresses anoikis.Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer.Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics.AMPK negatively regulates tensin-dependent integrin activity.Integrative systems and synthetic biology of cell-matrix adhesion sites.Quantitative profiling of spreading-coupled protein tyrosine phosphorylation in migratory cells.Multiplexed imaging of intracellular protein networks.A proteomics view on integrin-mediated adhesions.The cancer cell adhesion resistome: mechanisms, targeting and translational approaches.Integrin signaling in atherosclerosis.A Strong Contractile Actin Fence and Large Adhesions Direct Human Pluripotent Colony Morphology and Adhesion.Phosphoproteomics reveals network rewiring to a pro-adhesion state in annexin-1-deficient mammary epithelial cells.Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second.Proteomic Dissection of Nanotopography-Sensitive Mechanotransductive Signaling Hubs that Foster Neuronal Differentiation in PC12 Cells.Integrins promote axonal regeneration after injury of the nervous system.Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity.Cell adhesion is regulated by CDK1 during the cell cycle
P2860
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P2860
Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
Defining the phospho-adhesome ...... alysis of integrin signalling.
@en
type
label
Defining the phospho-adhesome ...... alysis of integrin signalling.
@en
prefLabel
Defining the phospho-adhesome ...... alysis of integrin signalling.
@en
P2093
P2860
P50
P356
P1476
Defining the phospho-adhesome ...... alysis of integrin signalling.
@en
P2093
David Knight
Joseph Robertson
Julian N Selley
Matthew C Jones
Stacey Warwood
P2860
P2888
P356
10.1038/NCOMMS7265
P407
P577
2015-02-13T00:00:00Z
P5875
P6179
1052361320