Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.

Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.

Item
http://www.wikidata.org/entity/Q38920601
Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?Oxidative stress management in the hair follicle: Could targeting NRF2 counter age-related hair disorders and beyond?Nrf2 is highly expressed in neutrophils, but myeloid cell-derived Nrf2 is dispensable for wound healing in mice.miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia.Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin.Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties.KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane.Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.Till Death Do Us Part: The Marriage of Autophagy and Apoptosis.C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosationFalcarinol Is a Potent Inducer of Heme Oxygenase-1 and Was More Effective than Sulforaphane in Attenuating Intestinal Inflammation at Diet-Achievable Doses
P2860

Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.

Item
http://www.wikidata.org/entity/Q38920601
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.
@en
type
label
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.
@en
prefLabel
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.
@en
P1433
P1476
P2093
P275
P2860
P304
P31
P356
P407
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants
@en
P2093
P275
P2860
P304
P31
P356
P407
P478
P50
P577
P698
P921
P932