Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways.
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High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticityAcetaminophen-induced Liver Injury: from Animal Models to HumansPathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicityMitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modificationsA cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophenAttenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in MiceAMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and FunctionReceptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis.FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagyHepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in MiceMechanisms of acetaminophen-induced cell death in primary human hepatocytes.Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.Autophagy protects against dasatinib-induced hepatotoxicity via p38 signaling.The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic CellsLiuweiwuling tablets attenuate acetaminophen-induced acute liver injury and promote liver regeneration in mice.Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in miceEnhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury.Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytesSchisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway.Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver.Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver.Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.Application of urine proteomics for biomarker discovery in drug-induced liver injury.The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance.Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy.Acetaminophen toxicity in rat and mouse hepatocytes in vitro.Natural Dietary Pigments: Potential Mediators against Hepatic Damage Induced by Over-The-Counter Non-Steroidal Anti-Inflammatory and Analgesic Drugs.Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.Interfering RNA against PKC-α Inhibits TNF-α-induced IP3R1 Expression and Improves Glomerular Filtration Rate in Rats with Fulminant Hepatic Failure.Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways.Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions.
P2860
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P2860
Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Protein kinase C (PKC) partici ...... ndependent signaling pathways.
@en
type
label
Protein kinase C (PKC) partici ...... ndependent signaling pathways.
@en
prefLabel
Protein kinase C (PKC) partici ...... ndependent signaling pathways.
@en
P2093
P2860
P356
P1433
P1476
Protein kinase C (PKC) partici ...... ndependent signaling pathways.
@en
P2093
Behnam Saberi
Derick Han
Heather S Johnson
Maria D Ybanez
Neil Kaplowitz
William A Gaarde
P2860
P304
P356
10.1002/HEP.26625
P407
P577
2014-03-03T00:00:00Z