Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.

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Staurosporine suppresses survival of HepG2 cancer cells through Omi/HtrA2-mediated inhibition of PI3K/Akt signaling pathway.Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells

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Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.

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2014 nî lūn-bûn

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Staurosporine analogs promote ...... all cell lung carcinoma cells.

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Staurosporine analogs promote ...... all cell lung carcinoma cells.

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Staurosporine analogs promote ...... all cell lung carcinoma cells.

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P1476

Staurosporine analogs promote ...... all cell lung carcinoma cells.

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Dominik Kraus

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Hichem Gallala

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Jochen Winter

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Michael Nowak

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Nadine Veit

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Rainer Probstmeier

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Sven Perner

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Viktor Janzen

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Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

A quantitative analysis of kinase inhibitor selectivity

A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer.

A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies

Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.

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Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage.

Lestaurtinib, a multitargeted tyrosine kinase inhibitor: from bench to bedside.

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s13277-014-2897-6

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2725-2735

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scholarly article

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10.1007/S13277-014-2897-6

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Cornelius Courts

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1046284000

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25487614

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Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.

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P2860

P2860

Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.

description

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P1433

P1476

P2093

P2860

P2888

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P31

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P433

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P6179

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P2093

P2860

P2888

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P356

P433

P478

P50

P577

P6179

P698