Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells.
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High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomibMolecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma.Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation.Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomibDDX53 Promotes Cancer Stem Cell-Like Properties and Autophagy.Bortezomib-Induced Muscle Toxicity in Multiple Myeloma.Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidanceProteasome inhibitors induce AMPK activation via CaMKKβ in human breast cancer cells.Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells.Autophagy: A New Mechanism of Prosurvival and Drug Resistance in Multiple Myeloma
P2860
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P2860
Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Bortezomib induces AMPK-depend ...... tosis in drug resistant cells.
@en
type
label
Bortezomib induces AMPK-depend ...... tosis in drug resistant cells.
@en
prefLabel
Bortezomib induces AMPK-depend ...... tosis in drug resistant cells.
@en
P2093
P2860
P356
P1433
P1476
Bortezomib induces AMPK-depend ...... ptosis in drug resistant cells
@en
P2093
Ehsan Malek
Sivakumar Vallabhapurapu
Subrahmanya Vallabhapurapu
P2860
P304
12358-12370
P356
10.18632/ONCOTARGET.2590
P407
P577
2014-12-01T00:00:00Z