Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
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Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary HepatocytesStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryRecapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytesDonor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.Transplantation of hESC-derived hepatocytes protects mice from liver injury.Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.Cell sources for in vitro human liver cell culture models.Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells.Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes.Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.Pluripotent stem cells to hepatocytes, the journey so far.Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signalling.Concise Review: Liver Regenerative Medicine: From Hepatocyte Transplantation to Bioartificial Livers and Bioengineered Grafts.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.In Vitro Generated Hepatocyte-Like Cells: A Novel Tool in Regenerative Medicine and Drug Discovery.Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Perfused Three-Dimensional Multicompartment Bioreactor.Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytesGene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.Reconstructing human pancreatic differentiation by mapping specific cell populations during development.Effects of Co-Culture Media on Hepatic Differentiation of hiPSC with or without HUVEC Co-Culture.Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics.De-liver CLiPs and revitalize hepatocytes.H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In VitroHuman hepatocyte transplantation for liver disease: current status and future perspectives.Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos.Human fetal liver cultures support multiple cell lineages that can engraft immunodeficient mice.Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes.Hepatic differentiation of human iPSCs in different 3D models: A comparative study.Liver 'organ on a chip'.Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction.Pluripotent Stem Cell-Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety.Phthalazinone Pyrazole Enhances the Hepatic Functions of Human Embryonic Stem Cell-Derived Hepatocyte-Like Cells via Suppression of the Epithelial-Mesenchymal Transition.Age-Related Epigenetic Derangement upon Reprogramming and Differentiation of Cells from the Elderly.Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells.Liver cell therapy: is this the end of the beginning?
P2860
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P2860
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Phenotypic and functional anal ...... rather than adult hepatocytes.
@en
type
label
Phenotypic and functional anal ...... rather than adult hepatocytes.
@en
prefLabel
Phenotypic and functional anal ...... rather than adult hepatocytes.
@en
P2093
P2860
P50
P1476
Phenotypic and functional anal ...... rather than adult hepatocytes
@en
P2093
Andrew A Berry
Charis-Patricia Segeritz
Chris E Goldring
Cliff Rowe
Fang Zhang
Hassan Malik
Joanne Henry
Lisa Mohamet
Marie Best
Melissa Baxter
P2860
P304
P356
10.1016/J.JHEP.2014.10.016
P407
P577
2014-10-18T00:00:00Z