The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.
about
Dissecting the Potential Interplay of DEK Functions in Inflammation and CancerDEK is required for homologous recombination repair of DNA breaks.The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners.DEK over-expression promotes mitotic defects and micronucleus formation.Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.The nuclear DEK interactome supports multi-functionality.Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management.The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival
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The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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name
The human oncoprotein and chro ...... eracts DNA replication stress.
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The human oncoprotein and chro ...... eracts DNA replication stress.
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The human oncoprotein and chro ...... eracts DNA replication stress.
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The human oncoprotein and chro ...... teracts DNA replication stress
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A Deutzmann
F Schönenberger
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10.1038/ONC.2014.346
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2014-10-27T00:00:00Z
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1000129472