Targeting CCR5 with siRNAs: using recombinant SV40-derived vectors to protect macrophages and microglia from R5-tropic HIV.
about
Pseudovirions as vehicles for the delivery of siRNACXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infectionPreintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy.Inhibition of multidrug resistance by SV40 pseudovirion delivery of an antigene peptide nucleic acid (PNA) in cultured cells.Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions.CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120Simian Virus 40 Infection in the Spinal Cord of Simian Immunodeficiency Virus-Immunosuppressed Rhesus MacaquesGenetic therapies against HIV.Specific transduction of HIV-susceptible cells for CCR5 knockdown and resistance to HIV infection: a novel method for targeted gene therapy and intracellular immunization.A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs.RNAi-directed inhibition of DC-SIGN by dendritic cells: prospects for HIV-1 therapy.Possible applications for replicating HIV 1 vectorsA novel approach to regulate experimental visceral leishmaniasis in murine macrophages using CCR5 siRNA.Replication-deficient rSV40 mediate pancreatic gene transfer and long-term inhibition of tumor growth.The Role of Natural Antibodies to CC Chemokine Receptor 5 in HIV Infection.
P2860
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P2860
Targeting CCR5 with siRNAs: using recombinant SV40-derived vectors to protect macrophages and microglia from R5-tropic HIV.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Targeting CCR5 with siRNAs: us ...... microglia from R5-tropic HIV.
@en
type
label
Targeting CCR5 with siRNAs: us ...... microglia from R5-tropic HIV.
@en
prefLabel
Targeting CCR5 with siRNAs: us ...... microglia from R5-tropic HIV.
@en
P1433
P1476
Targeting CCR5 with siRNAs: us ...... d microglia from R5-tropic HIV
@en
P2093
Barry Morse
David S Strayer
P304
P356
10.1089/154545703322616961
P577
2003-01-01T00:00:00Z