DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification.
about
The NF1 somatic mutational landscape in sporadic human cancers.Characterization of background noise in capture-based targeted sequencing data.Reference standards for next-generation sequencing.Alternative Chk1-independent S/M checkpoint in somatic cells that prevents premature mitotic entry.CScape: a tool for predicting oncogenic single-point mutations in the cancer genome.Ultra-sensitive Sequencing Identifies High Prevalence of Clonal Hematopoiesis-Associated Mutations throughout Adult Life.Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI).Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor.Ultraaccurate genome sequencing and haplotyping of single human cells.The York Gospels: a 1000-year biological palimpsest.Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.Next-generation sequencing of cytologic preparations: An analysis of quality metrics.A system for detecting high impact-low frequency mutations in primary tumors and metastases.Droplet digital PCR-based EGFR mutation detection with an internal quality control index to determine the quality of DNA.Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.Selective identification of somatic mutations in pancreatic cancer cells through a combination of next-generation sequencing of plasma DNA using molecular barcodes and a bioinformatic variant filter.Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.Metastasis of cancer: when and how?Tracing single-cell histories.Robust identification of mosaic variants in congenital heart disease.UDiTaS™, a genome editing detection method for indels and genome rearrangements.Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy.Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers.Detecting Rare Mutations and DNA Damage with Sequencing-Based Methods.Identification of somatic mutations in monozygotic twins discordant for psychiatric disorders.Mutational signatures and mutable motifs in cancer genomes.IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing.Somatic Mitochondrial DNA Mutations in Diffuse Large B-Cell Lymphoma.Sample-Index Misassignment Impacts Tumour Exome Sequencing.Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations.Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube FormatSolid-phase enzyme catalysis of DNA end repair and 3' A-tailing reduces GC-bias in next-generation sequencing of human genomic DNAHeterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testingTurning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets
P2860
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P2860
DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
DNA damage is a pervasive caus ...... unding variant identification.
@en
type
label
DNA damage is a pervasive caus ...... unding variant identification.
@en
prefLabel
DNA damage is a pervasive caus ...... unding variant identification.
@en
P2093
P2860
P50
P356
P1433
P1476
DNA damage is a pervasive caus ...... ounding variant identification
@en
P2093
Laurence M Ettwiller
Lixin Chen
Pingfang Liu
Thomas C Evans
P2860
P304
P356
10.1126/SCIENCE.AAI8690
P407
P577
2017-02-01T00:00:00Z