The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

about

Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences.The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells Alchemix, p53 and topoisomerase.

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The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

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2014 nî lūn-bûn

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The dual-acting chemotherapeut ...... independently of ATM and p53.

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The dual-acting chemotherapeut ...... h independently of ATM and p53

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A Thomas

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C Oldreive

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Cellular roles of dna topoisomerases: a molecular perspective

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

Acute lymphoblastic leukaemia

Targeting DNA topoisomerase II in cancer chemotherapy

Drugging topoisomerases: lessons and challenges

Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia.

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.

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onc.2014.266

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3336-3348

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scholarly article

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10.1038/ONC.2014.266

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English

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Grant S Stewart

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Klaus Pors

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chemotherapy

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

about

P2860

P2860

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

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